Severe Rickets with Multiple Spontaneous Fractures

Severe thalassaemia intermedia with multiple fractures: role of transfusion therapy.

Thalassaemia intermedia includes thalassaemias with clinical severity intermediate between asymptomatic thalassaemia minor and transfusion dependent thalassaemia major. By definition patients of thalassaemia intermedia maintain a haemoglobin level of 7-10 g/dl and do not, or only occasionally, require blood transfusion. An eight-year-old girl who was a known case of thalassaemia intermedia and ...

initial presentation of acute lymphoblastic leukemia with osteoporosis and multiple spontaneous bone fractures

Frequency of nutritional rickets in children admitted with severe pneumonia.

OBJECTIVE To determine the frequency of nutritional rickets in children hospitalized with severe pneumonia. METHOD This study was carried out at the department of paediatric medicine at National Institute of Child Health Karachi. It is a case series done over a period of six months from 15th November 2008 to 15th may 2009. Patients admitted (n=137) with severe pneumonia were included in the s...

Myelofibrosis in severe vitamin D deficiency rickets.

Vitamin D deficiency is prevalent in infants and children in the underdeveloped countries. Infants with mild deficiency tend to present with complications like hypocalcemic seizures whereas occurrence of pathological features in advanced rickets is well elucidated. Secondary myeloflbrosis has been reported as a complication of severe rickets and in these children anemia, myeloid metaplasia and ...

It is not always child abuse: multiple fractures due to hypophosphatemic rickets associated with elemental formula use

Rickets is not a disease of the past. We described a toddler who developed hypophosphatemic rickets associated with the use of elemental formula. This case highlights the importance of frequent monitoring of mineral metabolism in children receiving elemental formula and considering rickets in the workup of child abuse.